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3 Progress of Joint Research Activities
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Research No.: ㉒㉒ F-6 ODA Loan Joint Research Date: Oct. 8 , 2020
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1 General Title Biochemistry and pharmaceutical science in aquaculture and fisheries
Can Tho University: Tran Thi Tuyet Hoa (Leader), Pham Minh Duc, Bui Thi Bich Hang, Nguyen Thi Thu Hang,
Dang Thuy Mai Thy, Huynh Truong Giang, Tran Thi My Duyen, Nguyen Trong Tuan, Dai Thi Xuan Trang, Le Thanh
2 Core Members Phuoc, Nguyen Phuc Dam, Ngo Quoc Luan, Luu Thai Danh, Doan Van Hong Thien
Japanese Universities: KAMEI Kaeko (KIT), KANAORI Kenji (KIT)
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3 Duration Jan. 2018 – Dec. 2020 (3 years) <1 Batch>
Develop natural bioactive compounds in order to:
4 Main Objectives 1.Enhance of fish/ shrimp immune responses
2.Replace antibiotics/ chemicals in the prevention and treatment of aquatic animal diseases
5 Focal Points
1. Screening bioactive compounds to apply in drug production for the
prevention and treatment of aquatic animal diseases
Plant extracts 45 plant extracts
preparation were identified
Plant collection Powdered plant Mixture Evaporation Crude extracts
In vitro 6; 15; 14 and 6 plant extracts showed
h hiigghh aannttiimmiiccrroobbiiaall aaccttiivviittyy against 4
antimicrobial aquatic animal pathogens including A.
tests hydrophila, E. ictaluri, S. agalactiae
Paper disc Impregnated Spreading Placing Interpreting and V. parahaemolyticus, respectively
preparation paper disc bacteria impregnated disc result
Chemical analysis 11/20 pure compounds
and identification were identified
Crude Extracts showed high Chemical Component
extracts antimicrobial activity analysis identification
In vitro
antimicrobial tests Acute toxicity test
2 2.. AAsssseessssiinngg tthhee ppoossiittiivvee iimmppaacctt ooff nnaattuurraall bbiiooaaccttiivvee ccoommppoouunnddss iinn aaqquuaaccuullttuurree
E Evvaalluuaattiinngg tthhee aabbiilliittyy ttoo Plant extract In vivo Evaluating the ability of plant
test
• Enhance immunological extracts as immunostimulants
parameters and growth Mixing
performance Feeding and growth enhancer on
• Enhance the resistance to striped catfish, red tilapia,
pathogens in aquatic animals whiteleg shrimp and
Fish feed Challenging snakehead were done
D Deevveellooppiinngg aa pprroocceessss ttoo ssuupppplleemmeenntt
p prroodduuccttss wwiitthh bbiiooaaccttiivvee ccoommppoouunnddss iinn E Evvaalluuaattiinngg tthhee eeffffeeccttiivveenneessss ooff bbiiooaaccttiivvee
f feeeedd ffoorr ssoommee aaqquuaattiicc aanniimmaallss c coommppoouunndd pprroodduuccttss iinn ffaarrmmss
9 9//88 iinn VViieettnnaammeessee 2 2//22 PPhhDD 9 9//1122 MMSScc
Program outputs Program outputs 2 200 ppllaanntt ssppeecciieess && P Puubblliiccaattiioonnss 0 0//11 bbooookk 2 2//44 iinn 2 2//22 sshhoorrtt ttrraaiinniinnggss
j joouurrnnaall
1 1 sscciieennttiiffiicc rreeppoorrtt
1 166//1155 BBSScc
i inntteerrnnaattiioonnaall jjoouurrnnaall
e exxttrraacctt iiddeennttiiffiieedd
2 2 ddeevveellooppmmeenntt tteecchhnnoollooggyy &&
0 0//6600 ttrraaiinneeee
a apppplliiccaattiioonn tteecchhnnoollooggyy
6 Comments This research still continues towards finalizing program outputs.
ⓒ All Rights Reserved, Nov. 2020 (CTU)
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